Folate in a Biologically Active Form

• A combination of folic acid and vitamin B12 in their active forms
• Promotes cardiovascular health
• Required for DNA synthesis and important during pregnancy
• Clinically researched dosages

Folic acid (or folate) is vitamin B9, a water-soluble vitamin that plays a key role in DNA and RNA synthesis, red blood cell production, the metabolism of proteins, and healthy genetic expression. BioFolate contains L-5-methyltetrahydrofolate (L-5-MTHF), the active form of folate that is used in the body. Folate deficiency can cause a number of health problems, of which the most documented is neural tube defects in developing infants. Symptoms of folate deficiency include: weakness, fatigue, irritability, headaches, difficulties in cognitive function, mood imbalances, cramps, palpitations, shortness of breath, and can lead to more serious health problems.

Certain medical conditions can actually lead to secondary folate deficiencies through decreased absorption or an increase in the body’s demand for folate. These include alcoholism, Crohn’s disease, lymphoma or amyloidosis of the small intestine, diabetic enteropathy, gluten sensitivity, sickle cell disease, chronic exfoliative skin disorders and of course, pregnancy.

Additionally, a large percentage of the population has a certain gene mutation called MTHFR which renders them unable to convert dietary folate into the biologically active form, leading to folate deficiency. Taking folate in the form of L-5-MTHF ensures that even those with the MTHFR mutation are able to absorb the folate and avoid deficiency.  BioFolate also contains a small amount of vitamin B12 in the active form of methylcobalamin, since folate supplementation can mask a vitamin B12 deficiency.

DISCUSSION: BioFolate contains the preferred, biologically active form of folate that is produced in the body. BioFolate helps the body to metabolize carbohydrates, fats, and proteins and form red blood cells.

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